The Ego Trip by Kimon de Greef (with Dan Corder)

Loading player...
"There's patent litigation right now over the God molecule. I just think it's the most absurd thing."

What happens when an ethereal, ego-dissolving experience runs headlong into big pharma? Dan Corder chats to journalist Kimon de Greef on The Ego Trip, and the strange final act of the toad story: 5-MeO-DMT quietly becoming one of the smart bets to be the next clinical psychedelic treatment. They talk about why a half-hour trip is so seductive to a market-driven industry, the patent wars already breaking out over the God molecule, and the push to administer it without any accompanying psychotherapy at all. Kimon also makes a plea for the toads themselves, magnificent, grotesque creatures being tossed into buckets, over-milked and left in the sun as the movement they never asked to be part of goes global.

Kimon de Greef's new book is The Ego Trip: Psychedelic Toads, a Trail of Deaths, and the Guru Who Peddled Transcendence.

Kimon de Greef is one of the most important non-fiction writers working today. His work has appeared in National Geographic, The Guardian, The New Yorker and The New York Times, and his previous book, Poacher, drew wide acclaim.

Dan Corder is an award-winning political comedian, news commentator, TV, radio and podcast host.

The latest episode of Pagecast is out now!
11 Aug English South Africa Books · Society & Culture

Other recent episodes

Pagecast at OBF 2026: Natalie Sifuma and Alma-Nalisha Cele in conversation

Natalie Sifuma is a Kenyan writer, researcher, and consultant currently based in Cape Town. She is the founder of Sisters in Climate — a Pan-African climate initiative — and is completing an MPhil in Inclusive Innovation at UCT’s Graduate School of Business, with a focus on social impact, climate, and…
6 Sep 11 min

Pagecast at OBF 2026: Sahra Noor and Lethogonolo Mokogroane in conversation

On this installment of Pagecast at the 2026 Open Book Festival studio, Lethogonolo Mokogroane is joined by Sahra Noor. Sahra is a Somali-American writer whose work explores belonging, migration, and the complicated work of building a life across cultures. Alongside her writing, she works in global health, supporting efforts to…
6 Sep 16 min

Pagecast at OBF 2026: Faraaz Mahomed and Alma-Nalisha Cele in conversation

Kicking off Sunday at Open Book Festival 2026, Faraaz Mahomed joins Dr Alma-Nalisha Cele in the Pagecast studio. Faraaz is a researcher in the field of mental health and human rights, based between New York and his native South Africa. His short stories and travel writing have appeared in Granta,…
6 Sep 15 min

Pagecast at OBF 2026: Kirsten Deane and Letlhogonolo Mokgoroane in conversation

For the final recording on Saturday, Kirsten Deane joins Letlhogonolo Mokgoroane in the Pagecast studio at Open Book Festival 2026. Kirsten Deane is the lead editor of English Alive, South Africa’s oldest publication for high school students. Her writing has been published in journals nationally and internationally, and her debut…
5 Sep 16 min